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8, the highest negative binding free energy was noticed for the mh-Tyr-C3G docked complex ( 34.72 kcal/mol) by comparison to mh-Tyr-ARB inhibitor complex ( 7.23 kcal/mol) while docked complexes of mh-Tyr-EC (12.84 kcal/mol) and mh-Tyr-CH complex (3.1 kcal/mol) exhibited a net positive binding energy

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They determined that those prescribed GLP-1 agonists exhibit a significantly lower risk of developing RVO over five years, particularly for branch RVO (BRVO), compared to those on DPP-4 inhibitors, which could contribute to favorable long-term ocular outcomes and reduce the burden of visual impairment with this treatment option in this population