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Pernicious anemia often leaves individuals feeling exhausted and weak, as a lack of B12 prevents the body from producing enough red blood cells, which are responsible for carrying oxygen to tissues and organs

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USP guidance describes a 28-day beyond-use date for multi-dose vials after first puncture, assuming aseptic technique on every draw

And it sounds like that's kind of what you're seeing as well

Frequently Asked Questions How long does it take for vitamin B12 to relieve nerve pain

What needle gauge should I use