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SKU: 94430002675

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EUR24.82 EUR60.82

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Description

145 F-box protein FBXL2, known as a negative regulator of stemness by targeting the transcription factor E47 for polyubiquitination and proteasome-mediated degradation in breast cancer, is significantly down-regulated in paclitaxel-resistant TNBC cells

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The enzyme activity pH dependence and bonding interactions in the active site suggest that the catalytic His 18 is protonated in UGT74F2 to form SGE, while SAG formation in UGT74F1 requires the deprotonated His 18

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As of 2023 there were 3,536 total Lots. Of those 3,536 Lots, 189 were owned by the County or the Association

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