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References Hayes JD, Pulford DJ

Didangelos, T., Karlafti, E., Kotzakioulafi, E., Margariti, E., Giannoulaki, P., Batanis, G., Tesfaye, S., & Kantartzis, K

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Diagnostics, 8 (4), 70

At Perfect B in Doral, FL, we see patients regularly who tried oral or sublingual sermorelin before coming in, and the pattern is consistent: no change in body composition, no improvement in sleep quality, and no measurable rise in IGF-1

However, for most agents, including warfarin and digoxin, overall systemic exposure is not clinically meaningful, and routine dose adjustments are generally unnecessary