Tirzepatide acts on two (GLP-1 and GIP), which in clinical studies has been associated with greater average weight loss
Muscle tissue burns calories at rest, helps with insulin sensitivity, and keeps you strong for daily activities
Both are weekly injectable treatments used as part of a medically supervised weight loss programme, alongside lifestyle changes and follow-up
Tirzepatide is sold as Mounjaro and Zepbound, while semaglutide is sold as Ozempic, Wegovy, and Rybelsus
Semaglutide use and weight loss Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that Three brand names for semaglutide have been approved by the Food and Drug Administration (FDA) for different purposes: Wegovy: FDA-approved for weight loss and reducing the risk of cardiovascular disease
Wang X, Yu S, Hu JP et al (2014) Streptozotocin-induced diabetes increases amyloid plaque deposition in AD transgenic mice through modulating AGEs/RAGE/NF-B pathway