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Many studies indicate an association between increased VEGF expression in the brain, brain hypoperfusion, and increased BBB permeability, which increases unwanted angiogenesis, and may favor the occurrence of neurodegenerative diseases (Chen et al

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Horm Metab Res 27:372375 Slavin BG, Ong JM, Kern PA (1994) Hormonal regulation of hormone-sensitive lipase activity and mRNA levels in isolated rat adipocytes