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Side effect preparation: Nausea is the most reported side effect, particularly during the first four to eight weeks as doses increase

Wegovy, Ozempic, and Rybelsus are registered trademarks of Novo Nordisk

Many patients experience improvement as their bodies adapt to the medication, though this adaptation may take longer than 8 weeks, particularly during Wegovy's 16-week titration period

Semaglutide for weight loss is not appropriate for everyone

For example, in the STEP 1 trial, participants receiving semaglutide 2.4 mg weekly showed improvements in insulin sensitivity markers that correlated with the degree of weight loss achieved after 68 weeks of treatment