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Rather than developing another pure GLP-1 agonist, Lilly pursued a dual-mechanism approach targeting both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

Because of the way patents for small peptides work, anyone can make a small change to a molecule, adding one amino acid here or there and now have a competing product that would not fall under the patent

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doi: 10.3389/fendo.2021.736867 18 WilliamsABabuJRWadsworthDDBurnettDGeethaT