In summary, we found that KG was required for histone acetylation via TMHLE-catalyzed carnitine synthesis to facilitate HR-mediated DNA repair in CCNE1-driven models
In contrast, dietary LCFAs drive nave T cell polarization toward Th17 cells through p38 MAPK signaling, aggravating pathology in experimental autoimmune encephalomyelitis (9698)
Eur J Clin Nutr 72(1):2637
Eradicating bacterial persisters with combinations of strongly and weakly metabolism-dependent antibiotics
Camel Milk Cannot Prevent the Development of Cow's Milk Allergy-A Study in Brown Norway Rats
TMP269, a potent and selective class IIa HDACs inhibitor, significantly improves the pathological changes including renal tubular dilation, cell debris accumulation in the renal tubular lumen, interstitial edema, and inflammatory cell infiltration in FA-/IRI-induced AKI mouse model by reducing the expression of HDAC4 to regulate pathways associated with apoptosis, autophagy, and proliferation
