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[DOI] [PubMed] [Google Scholar] 130.Vollmer J.P., Haen S., Wolburg H., Lehmann R., Steiner J., Reddersen S., Fend F., Fallier-Becker P

Because of the potential for serious adverse reactions in a breastfed infant, including the potential for empagliflozin to affect postnatal renal development, advise patients that use of SYNJARDY or SYNJARDY XR is not recommended while breastfeeding

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Specifically, the 12 mg arm of retatrutide has shown the highest discontinuation figures of the three compounds at their respective top doses, though investigators have suggested that part of the rate reflects participants who reached weight loss thresholds and chose to discontinue