Processing these datasets yielded consensus maps with global resolutions of 3.3 (oxyntomodulin) and 3.7 (exendin-4) at gold standard FSC 0.143 (Figure 1B-C, Supplemental Figure 1)
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Furthermore, treatment with Pluronic L-81, a surfactant that inhibits chylomicron formation, significantly attenuates the anorectic effects of intraduodenal lipids and attenuates both CCK release and celiac and cervical vagal afferent activation following lipid infusion 40,109,156,186
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