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Revised Date: January 18, 2023 Recommendations and Topics Scope Key Recommendations Background Epidemiology Patient Risk Factors Associated with B 12 Deficiency Patient Risk Factors Associated with Folate Deficiency Prevention Diagnosis Management Ongoing Care References Resources Appendix A: Dietary sources of cobalamin Scope This guideline covers the primary care investigation and management of cobalamin (vitamin B 12 or simply B 12 ) and folate deficiency in adults

Postnatal Supplements As evident in Table 2, there is high variability both between the components of prenatal and postnatal supplements and within these groups themselves

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From there, its influence extends into connective tissue, the vasculature, and the central nervous system through mechanisms that are now being characterized at the molecular level

Proton Pump Inhibitors (PPIs): Medications like omeprazole (Prilosec) reduce stomach acid