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Since semaglutide can also impact kidney function, using NSAIDs for long periods may increase your risk of high potassium

Wen S, Ma D, Zhao M, Xie L, Wu Q, Gou L, et al

These changes, though not classically classified as AEs, can have important implications for metabolic health and physical function, and their magnitude appears to vary depending on factors such as baseline nutritional status, physical activity, and adherence to dietary interventions

Foods (Basel, Switzerland), 11 (23), 3934

In addition, it regulates glucose production in the liver

Like Wegovy, insurance plans usually wont cover Saxenda without prior authorization