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It plays several roles in digestion, appetite regulation, and blood sugar control
it represents the body approaching a new set point where energy intake and expenditure reach equilibrium
The primary mechanism of action involves stimulating insulin secretion from pancreatic beta cells in a glucose-dependent mannermeaning it only triggers insulin release when blood sugar levels are elevated
The EMA European Public Assessment Reports (EPARs) for Wegovy, Ozempic, and Mounjaro provide further detail on the GI safety profiles of these approved agents and represent the most authoritative class-level evidence currently available
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