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However, it is disappointing that IGF-1 has not been shown to play a very significant role in promoting tendon healing in clinical trials, which could reflect our poor understanding of the molecular mechanisms by which IGF-1 is involved in promoting tendon regenerative healing

Melton R, Thomas R, Vollmer P

doi: 10.1016/j.ccc.2020.11.001 150 ZarbockANadimMKPickkersPGomezHBellSJoannidisMet al

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Experimental studiesin vivo Given that SLC2A9 contributes to UA blood levels through its activity in the kidney, other processes inevitably mediate the influence of serum UA on the risk or progression of a brain disease such as PD