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however, women should be informed that metformin crosses the placenta, longer-term studies are not yet available, and the addition of insulin is necessary in approximately 40% to achieve adequate glycemic control [Grade D, Consensus]

10.1007/s11892-018-0976-6 299 SchliessF.Von DahlS.HaussingerD

Maintaining leg strength becomes especially important to prevent falls and support daily activities