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Kidney disease If you have kidney problems, you must not take magnesium supplements without medical supervision, as your kidneys may not be able to clear excess magnesium from your blood, leading to toxic levels

Last updated 3/2025

Although those benefits have been demonstrated only for specific OMMs (that is, tirzepatide for OSAS and semaglutide for KOA), it is plausible that these effects are largely driven by weight reduction rather than by unique pharmacodynamic properties of each molecule 55,56

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Zepbound can also cause gall bladder or pancreas problems, so anyone who has severe stomach pain or pain that is associated with vomiting needs to see their doctor right away, Dr

PMCID: PMC7566932