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Subcutaneously administered tirzepatide vs semaglutide for adults with type 2 diabetes: a systematic review and network metaanalysis of randomised controlled trials

Timeline and Duration of Ozempic-Related Diarrhea Diarrhea typically emerges within the first 2-4 weeks of starting semaglutide or during dose escalation phases, when your body encounters the medication's effects for the first time or at a higher intensity

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These agents include Rybelsus (oral semaglutide) and the novel first-in-class dual GIP/GLP-1 receptor agonist Mounjaro (tirzepatide), which is now available for use in the management of type 2 diabetes