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Chronic unpredictable stress, considered a model of depression, results in a reduction in dendritic lengths and branching of apical dendrites, the loss of functional synaptic spines, and the reduction of dendritic complexity in PFC neurons and in the hippocampal CA3 pyramidal neuronal cell layer (McEwen et al., 2012
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PMCID: PMC6982879
GHK-Cu and Anxiety One study found that intraperitoneal administration of GHk-Cu before the elevated maze test decreased anxiety in rats
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