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StatPearls Publishing

doi: 10.1530/eje.0.1440251 104 MazziottiGGiustinaA

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At week 4, women in the treatment group displayed improved skin elasticity (+12.7%), reduced wrinkle volume (16.5%), decreased transepidermal water loss (10.8%), increased hydration (+3.5%), and enhanced collagen density compared with baseline values (measured via specialized skin analysis instrumentation)

Overexpression of IGF-1 in muscles causes an increase in muscle size

The gap between theoretical potential and practical results drives continued experimentation with dosing protocols