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The main enzymes involved in enzymatic reactions are uncoupled endothelial nitric oxide synthase (eNOS), NADPH oxidase (NOX), xanthine oxidase (XO), arachidonic acid (ARA), peroxidase, and metabolic enzymes such the cytochrome P450 system, cyclooxygenase, and lipoxygenase

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Tirzepatide, a dual GLP-1 and GIP receptor agonist, has demonstrated average weight loss of 2022% in clinical trials