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Most importantly, this protective phenotype appears to involve the following beneficial cellular adaptions: (i) enhanced metabolism of ethanol and acetaldehyde, (ii) suppression of lipogenic genes and induction of genes involved in fatty acid oxidation, and (iii) induction of the NRF2 antioxidant response and the AMPK metabolic signaling pathway

This mechanism has particularly important implications for wound healing research

For instance, in individuals diagnosed with irritable bowel syndrome (IBS), adopting a low-FODMAP diet has demonstrated efficacy in alleviating symptoms such as abdominal pain and bloating (Black et al., 2021)

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However, the lack of extensive clinical trials specifically targeting its use in pregnant women raises questions about its safety and efficacy