Simultaneous application of cisplatin and erastin synergistically induces ferroptosis in colon and lung cancer cells ( Recently, the role of p53 biology in ferroptosis has received increasing interest for novel cancer treatments (Jiang et al., 2015)
A logic-incorporated gene regulatory network deciphers principles in cell fate decisions
Alpha-lipoic acid upregulates the PPAR/NRF2/GPX4 signal pathway to inhibit ferroptosis in the pathogenesis of unexplained recurrent pregnancy loss
Genius Ditz: Old Man Jenkins may be a complete buffoon, but he sure knows how to run his farm
FOXO4-DRI has been investigated extensively in preclinical academic literature for p53 transactivation domain binding, senescence-associated apoptosis pathway research, p16 and IL-6 marker dynamics in senescent cell research models, and SASP (senescence-associated secretory phenotype) signaling
Oxidation of dopamine and consequent quinone modification contribute to the vulnerability of dopaminergic neurons ( Mitochondrial Dysfunction Neuronal ATP formation depends on mitochondrial aerobic respiration, which normally produces hydrogen peroxide and superoxide radicals as byproducts during mitochondrial oxidative phosphorylation (5)