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10.1016/j.exer.2014.09.010 36.0 36.1 Kennedy DO: B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review

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Even though some patients have mutations in TARDBP , the gene that codes for TDP-43 protein, not all TDP-43 pathologies are associated with the mutation 10 , and not all protein accumulations occur in the cytoplasm, some are detected in the nucleus 11, 12

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Our findings demonstrate that the reaction conditions can be flexibly optimized not only for the synthesis of proteins with disulfide bonds but also for proteins requiring a reduced state