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2 Most people with MS are diagnosed between ages 20 and 50, and women are approximately 2.5 times more likely to develop the condition than men

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Although recent comprehensive functional genomics work has shed light on how OCTN2 missense variants affect both carnitine transport and membrane localisation 11 , the mechanism of carnitine transport and how clinically relevant variants affect transport at a molecular level are yet to be determined

They are not clinical conclusions and not statements of therapeutic effect

Cysteine is a valuable carbon source, since its catabolism produces organic compounds such as pyruvate, -ketobutyrate, glutamate, serine, propionyl-CoA, succinate, and acetyl-CoA which supply the TCA cycle, and are intermediates for fatty acid synthesis (54, 55)

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