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Concordance among monozygotic twins is 25% (in fact lower than in migraine, schizophrenia and even infectious diseases such as poliomyelitis and tuberculosis, see below

It also expresses aromatase, which converts androgens into estrogen

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Serious symptoms are uncommon but need medical attention, including significant swelling, chest pain, shortness of breath, sudden vision changes, allergic reaction symptoms, or major mood changes