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This means less NAD+ is being produced

GLP-1 medications may not be appropriate for some patients

In addition, palmitoyl-CoA, steroid hormones and diethylstilbestrol (DES) are also inhibitors of mammalian GDH, but their binding sites are unknown

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The efficacy of GLP-1 analogues on appetite parameters, gastric emptying, food preference and taste among adults with obesity: Systematic review of randomized controlled trials