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d , mRNA and protein levels of GGT isoforms in the cell line HCC-1806, using data from (b) and (c)

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These are then reassembled in cells that need themor used as standalone amino acids

While directly measuring neuroprotection in living patients is technically unfeasible, alternative strategies, such as monitoring pro-inflammatory markers or neuroprotective cytokines in the plasma of patients receiving istradefylline, could offer valuable mechanistic insights and serve as surrogate indicators of therapeutic activity [485]