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Indeed, the term GSTome has been coiled to reflect the entire collection of all Gsts and their roles in an organism 46

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Utilizing CDCA, an endogenous bile acid, this system activates the nuclear receptor farnesoid X receptor (FXR) and the membrane receptor Takeda G protein-coupled receptor 5 (TGR5), consequently facilitating FAO, lipolysis, and mitochondrial bioenergetics [320, 321]

However, your provider will evaluate your medication list to ensure there are no interactions

However, these approaches face critical delivery challenges, including poor tumor penetration, rapid systemic clearance, and off-target toxicity, necessitating nanomaterials-mediated targeted delivery systems to achieve tumor-specific accumulation and enhanced therapeutic precision