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MiR-125 also regulates the cholinergic functions via modulating CLOCK gene

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This can lead to the depletion of glutathione, further compromising the body's ability to detoxify toxins and heavy metals

[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Jomova K, Valko M

For instance, Kabir et al stated that Cd (10 M CdSO 4 ) significantly declines elemental concentration, photosynthetic performance, and biomass yield in sugar beet [9]

123,124 Therefore, all the pathways and metabolic reactions in which NAD is involved are also altered by aging, and this decreased metabolic activity has been associated with numerous aging-related metabolic diseases, such as diabetes