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Massey, V., Williams, C
Patients should monitor their skin regularly and seek dermatology evaluation for any new, changing, or concerning lesions
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Site-specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening
The unmodified parent compound, recombinant human IGF-1 (mecasermin), is FDA-approved (2005) for severe primary IGF-1 deficiency and Laron syndrome in pediatric patients, but the modified LR3 analog itself has not been advanced into clinical development
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