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The FDA prescribing information notes that tirzepatide is not recommended for patients with severe gastrointestinal disease, including severe gastroparesis

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Staying aware of how both blood sugar and potassium are reacting is important to avoid complications

Some patients may experience a transient increase in acne or rosacea-like skin reactions, thought to be related to the effects of vitamin B12 on skin bacteria, though this is uncommon and typically mild