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But often it come with gastrointestinal side effects and higher costs

Research demonstrates distinct differences in their effectiveness, safety profiles, and associated costs

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Cysteine residues in Keap1 act as sensors for electrophiles and oxidants, and their oxidation leads to the release and subsequent translocation of Nrf2 into the nucleus where it can bind to the ARE4 sequence in the promoter region of genes involved in antioxidant defense (Moinova and Mulcahy 1999)

These drugs act by limiting the availability of lipids and consequently reducing proliferation [12, 13]

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