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Because B12 is naturally present only in meat and other animal products, vegans and vegetarians may not get enough B12 from their diet

Hydroxocobalamin binds more tightly to serum proteins, creating a depot effect that allows for slower release and prolonged availability to tissues

These nerve-related changes can occur even without anemia being present, which means standard blood counts alone may not catch a developing deficiency

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Helps maintain sterility of reconstituted solutions when accessed multiple times using aseptic technique

This is in very severe cases