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[69] found in an animal model that dietary calcium had a beneficial effect on lipoprotein profile by upregulating the mRNA levels of intestinal ABC G5/G8 and cholesterol-7-hydroxylase (CYP7A1), whereas it downregulated the intestinal NCP1-L1 and microsomal triacylglyceride transport protein (MTP) due to enhanced biliary cholesterol excretion

The inhibition of IL-4 or its receptor in mouse paradigms of allergen-sensitized asthma has been demonstrated to reduce pulmonary swelling, blood IgE concentrations, and bronchial hyperactivity to cholinergic drugs (i.e., methacholine)

it also targets your brain

See: Roche/Carmot

doi: 10.3389/fnagi.2019.00177 Received 28 February 2019 Accepted 02 July 2019 Published 08 August 2019 Volume 11 - 2019 Edited by Anne Eckert, University Psychiatric Clinic Basel, Switzerland Reviewed by Patrizia Giannoni, University of Nmes, France

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