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Perillo B, Di Donato M, Pezone A, Di Zazzo E, Giovannelli P, Galasso G, et al

Eczema skin often shifts to a higher pH, which favors S

This state functionally extends the gutliver axis to peripheral tissues, thereby giving rise to additional inter-organ communication axes, such as the gutliverhoof axis 172

Selective modulation of the nitric oxide system balances beneficial vasodilation against inflammatory damage, creating optimal healing conditions

Stimulated B and T cells can migrate to the blood (IgE and the allergen are distributed throughout the body with bodily fluids), and they are transported back to mucous membranes and the associated lymphatic structures (mainly GALT) where the allergen was first encountered