Its status varies depending on country, purpose of use, and sports organization regulations
Obesity A recent meta-analysis, summarized studies focused on LC supplementation for a prolonged time (median 3 months) [40]
When the meiotic spindle, the cellular machinery that pulls chromosomes apart, doesn't receive adequate energy, chromosomes are more likely to be distributed unequally, producing aneuploid eggs
A separate 2024 study reached a similar conclusion and credited the hydrating benefits to its film-forming properties
The results suggest that HTYs in vivo cardioprotective effects may be mediated in part by its circulating metabolites rather than the parent molecule, therefore, the demonstrated signaling modulation of free HTY effects should be interpreted as indirect modulation through oxidative stress-related markers rather than direct plaque-regressive action
Chronic obstructive pulmonary disease (COPD) Clinical correlation analysis shows that LONP1 protein expression in the airway epithelium of patients with severe COPD is markedly reduced compared with healthy individuals, and its expression level negatively correlates with the squamous metaplasia score [74]