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Cagrilintide is a long-acting amylin analogue with dual amylin and calcitonin receptor activity, whereas semaglutide is a once-weekly GLP-1 receptor agonist with robust anti-hyperglycemic and appetite-suppressing effects

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The glucagon receptor activation drives hepatic fat oxidation in ways that dual agonists do not replicate

10.1016/j.imlet.2020.02.012 Immunol

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