Longer use may blunt responsiveness due to IGF-1 receptor downregulation
Its often the peptide of choice for those who want faster or more noticeable results
While Ipamorelin brings clean and selective GH release without the cortisol and prolactin spikes that plague other secretagogues
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Research shows ipamorelin stimulates insulin release from the pancreas, which could actually be beneficial, but effects on long-term glucose control need monitoring through regular bloodwork