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A review, Exp

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Supernatant was collected and purified by solid-phase extraction using Oasis HLB 1cc (30 mg) SPE columns (Waters)

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Unexpectedly, we found that GLP-1 WT bound human FcRn 5-fold more strongly than unfused WT albumin at acidic pH, due to both faster association and slower dissociation

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[PubMed: 13821167] 293

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In the context of perimenopause-driven insulin resistance, it may serve as both a metabolic intervention and a longevity tool

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