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While patients with large and giant CMN have the greatest overall lifetime risk of melanoma, estimated between 4.5 % and 10 % [5], all congenital nevi should be considered as potential precursor lesions and patients and parents should be educated to monitor for changes in appearance

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This review explores the converging mechanisms through which estrogens and GLP-1RAs may act synergistically to prevent or delay the onset of AD

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