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Furthermore, Nalm6 cells lacking FANCB were significantly sensitive to GSH inhibition even in the absence of FA, which might be a consequence of an increase in endogenous free FA, overall suggesting that GSH supply might be fundamental for Fanconi Anaemia patients (Fig

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Indeed, we may be witnessing a protective effect on the liver associated with a further exposure of the tumour cells to ROS-induced necrosis/apoptosis

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