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Methods: A transverse aortic constriction (TAC) model of myocardial hypertrophy was established in vivo using C57BL/6 mice, while neonatal murine cardiomyocytes were stimulated with phenylephrine (PE) as an in vitro validation model system

Scott-Jones J

first proposed the concept and composition of inflammasomes: (1) pattern-recognition receptors (PRR) or NOD-like receptors (NLR) or AIM2-like receptors (ALR)

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Additionally, probiotics may increase serum vitamin D 3 levels and assist in the prevention of bone loss