When considering efficacy, GLP-1 RAs alone are generally insufficient for treating moderate or severe hypertension, but they can meaningfully improve BP in patients whose levels are just above goal despite standard therapy
Plus, it helps to promote collagen production and cell regeneration
Du Y, Xia L, Jo A, Davis RM, Bissel P, Ehrich MF, et al
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1 = Glucagon-like peptide 1
doi:10.2337/dc24-SINT Davies MJ, et al
The results showed that VRK2 knockdown could induce an increase of ROS and decline of cell viability and GSH following TBHP treatment, while these alterations could be partly reversed by ectopic SLC7A11 expression but not GCLC or GSS expression (Fig