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Lets look at the main factors to consider: Bioavailability Traditionally, injection has been considered the most efficient route of administering peptide drugs due to their instability and rapid degradation with oral, topical, and other delivery methods

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Mental Health: Antidepressants and anxiolytics are heavily prescribed

Food and Drug Administration has not approved for the treatment of insomnia, sleep disorders, or any other medical condition

doi: 10.3389/fphar.2021.760581 Received 18 August 2021 Accepted 17 September 2021 Published 26 October 2021 Volume 12 - 2021 Edited by Xuefeng Li, Guangzhou Medical University, China Reviewed by Xiangling Meng, Stanford University, United States Yitian Xu, Houston Methodist Research Institute, United States Qiang Qin, University of Texas MD Anderson Cancer Center, United States Dandan Zhu, University of Texas Health Science Center at Houston, United States Updates Copyright 2021 Wang, Wang, Liao, Hu, Chen, Meng, Gao and Li