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Kelly et al

Kang may combine targeted spinal injections with an IV infusion to calm nerve sensitivity throughout the body

5 months Result:Significantly reduced high-selenium-induced weight gain compared to the high-selenium alone group, with final body weight closer to the adequate-selenium control group

Cellular communication pathways

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It has been found that oxidative stress negatively impacts mitochondrial biogenesis, and increased HO-1 expression can upregulate peroxisome proliferator-activated receptor-gamma coactivator 1 alpha and promote mitochondrial biogenesis (70, 75)