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Furthermore, a controlled investigation identified mitochondrial malfunction in 80% of ASD children, despite that only 20% of these children had increased lactate levels, and only 10% had mitochondrial dysfunction [72]

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In recent years, several protocols have been developed using Agrobacterium tumefaciens and Agrobacterium rhizogenes as gene delivery systems ( Figure 6 )

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Absence of palmitoylation on IFNAR1 Cys463 selectively affects STAT2 activation, leading to incompetent STAT1 activation and nuclear translocation with a concurrent reduction in IFN--activated gene transcription

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