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New finding as alternative obesity treatment: PL inhibitory peptides approaches The previous study explores the potential of natural peptides as inhibitors of pancreatic lipase, aiming to contribute to obesity treatment

The article says this makes it harder to tell which agent is responsible for any adverse event

doi: 10.1016/j.heliyon.2025.e42029 115

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These include reduced GHRH or ghrelin secretion, greater somatostatin inhibition, greater somatotroph sensitivity to IGF-I feedback, reduced pituitary responsiveness to GHRH, and reduced pituitary or hypothalamic responsiveness to ghrelin