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Upon receptor binding, it initiates Gq-coupled intracellular signaling, thus activating phospholipase C, generating inositol trisphosphate, and mobilizing intracellular calcium

The putative role of neuroinflammation in the complex pathophysiology of migraine: from bench to bedside

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Pharmacological inhibition of NNMT significantly shows benefits diet-induced obese mice, including reducing the body weight gain and adipocyte size, and decreasing serum cholesterol levels