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Retatrutide achieved up to 24.2% body weight reduction in 48 weeks in Phase 2, and the recently completed Phase 3 TRIUMPH-4 trial pushed that number to an unprecedented 28.7% at 68 weeks

This is encouraging and has potential to be relevant when considering prescribing choices to lower ICP

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Figure 7 Autonomic dysfunction, vasoconstriction, and hypoxia Many ME/CFS patients have a unique cardiovascular situation (58) and changes indicative of autonomic dysfunction (329331)

BPC-157 restored function after sciatic nerve transection and regulated dopaminergic tone in neuroinflammatory models. Perovic, D